Characterization of a Novel Packaged Hydrogel Wound Dressing by 2.35 T Magnetic Resonance Imaging
نویسندگان
چکیده
Hydrogel wound dressing makes easier the treatment of patients suffering from difficult wounds. A new process for manufacturing a sterile, packaged hydrogel dressing, based on an interpenetrating structure calcium alginate, agar, and polyvinylpyrrolidone, was recently developed. The formulation overtakes some previous technologies’ drawbacks expressing better resistance to mechanical deformations compared products market. In this work, 2.35 T proton density, spin-lattice relaxation time, spin-spin phase-coherence relaxation, water apparent diffusion coefficient analysis in several alternative formulations, including commercial one (Neoheal®), are reported. Specifically, combination acting as thermolabile forming agent, with alginate γ irradiated acting, respectively, physical, chemical crosslinking agents irreversible (temperature independent) effect, have been investigated. brings qualitative improvement its handling due increased stiffness when reference. This comes together reduced content (100 vs. 112 density arbitrary units) swelling capacity (88% 124%) but improved mobility (1.42 1.34 × 10−3 mm2 s−1 coefficient).
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ژورنال
عنوان ژورنال: Electronics
سال: 2022
ISSN: ['2079-9292']
DOI: https://doi.org/10.3390/electronics12010188